Copper-Catalyzed para–Selective C–H Amination of Electron-Rich Arenes

Berzina, B.; Sokolovs, I.; Suna, E. ACS Catalysis 2015, 5, 7008–7014.

DOI: 10.1021/acscatal.5b01992

Abstract

A one-pot two-step method for para-selective C–H amination of carbocyclic arenes comprises the in situ formation of unsymmetrical diaryl-λ3-iodanes followed by their Cu(I)-catalyzed reaction with a range of N-unprotected amines.