Development of a Chiral DMAP Catalyst for the Dynamic Kinetic Resolution of Azole Hemiaminals

Kinens, A.; Sejejs, M.; Kamlet, A. S.; Piotrowski, D. W.; Vedejs, E.; Suna, E. J. Org. Chem. 2017, 82, 869–886.

DOI: 10.1021/acs.joc.6b02955

Abstract

A new catalyst for the dynamic kinetic resolution of azole hemiaminals has been developed using late-stage structural modifications of the tert-leucinol-derived chiral subunit of DMAP species.


DATE: Jan 6, 2017
AUTHOR: Artis Kinens
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