Dr. Dmitrijs Lubriks

Dr. Dmitrijs Lubriks

Former PhD student, Project Leader

dmitrich at osi d0t lv

Curriculum Vitae

Born

June 20th, 1983

Education

PhD in chemistry, Riga Technical University, 2015
Thesis: “Discovery of mPGES-1 inhibitors. Development of methods for C-H acetoxylation and amination of (hetero)arenes”
Supervisor: Prof. E. Suna

MSc in chemistry, Riga Technical University, 2007
Thesis: “Synthesis of polyfunctionalized indolylmagnesium species”
Supervisor: Prof. E. Suna

Experience

Latvian Institute of Organic Synthesis
Research Scientist, 2015-present
Research Assistant, 2007-2015
Laboratory Assistant, 2002-2007

Publications

  1. Dumont, E.; Vergalli, J.; Pajovic, J.; Bhamidimarri, S. P.; Morante, K.; Wang, J.; Lubriks, D.; Suna, E.; Stavenger, R. A.; Winterhalter, M.; Refregiers, M.; Pages, J. M. “Mechanistic aspects of maltotriose-conjugate
    translocation to the Gram-negative bacteria cytoplasm” Life Science Alliance 2019, 2, e201800242. DOI: 10.26508/lsa.201800242
  2. Sokolovs, I.; Lubriks, D.; Suna, E. “Copper-Catalyzed Intermolecular C-H Amination of (Hetero)arenes via Transient Unsymmetrical lambda3-Iodanes”  J. Am. Chem. Soc. 2014136, 6920–6928. DOI: 10.1021/ja502174d
  3. Lubriks, D.; Sokolovs, I.; Suna, E. “Indirect C–H Azidation of Heterocycles via Copper-Catalyzed Regioselective Fragmentation of Unsymmetrical λ3-Iodanes” J. Am. Chem. Soc. 2012134, 15436-15442DOI: 10.1021/ja305574k
  4. Lubriks, D.; Sokolovs, I.; Suna, E. “Iodonium Salts Are Key Intermediates in Pd-Catalyzed Acetoxylation of Pyrroles” Org. Lett. 201113, 4324-4327. DOI: 10.1021/ol201665c

Patents

  1. Priepke, H.; Doods, H.; Kuelzer, R.; Pfau, R.; Stenkamp, D.; Pelcman, B.; Rönn, R.; Lubriks, D.; Suna E. Imidazo(4,5-b)pyridine-6-carboxamides as anti-inflammatory agents. WO2012/076674 A1, 14 June, 2012
  2. Priepke, H.; Kuelzer, R.; Mack, J.; Pfau, R.; Stenkamp, D.; Pelcman, B.; Rönn, R.; Lubriks, D.; Suna E. 2-Aminobenz imidazole derivatives useful in the treatment of inflammation WO2012/076672 A1, 14 June, 2012
  3. Priepke, H.; Doods, H.; Kuelzer, R.; Pfau, R.; Stenkamp, D.; Pelcman, B.; Rönn, R.; Lubriks, D.; Suna, E. 2-(Arylamino)-3H-imidazo-[4,5-b]-pyridine-6-carboxamide derivatives and their use as MPGES-1 inhibitors. WO2012/022792 A1, 23 February, 2012
  4. Pfau, R.; Arndt, K.; Doods, H.; Klinder, K.; Kuelzer, R.; Lubriks, D.; Mack, J.; Pelcman, B.; Priepke, H.; Rönn, R.; Stenkamp, D.; Suna, E. 3H-Imidazo-[4,5-c]-pyridine-6-carboxamides as anti-inflammatory agents. WO2010/100249 A1, 10 September, 2010