Stereoselective synthesis of Doxapram

A method for large-scale synthesis of generic drug Doxapram has been developed in collaboration with Galleon Pharma, Inc. (USA)

Patents:

  1. Dax, S.L.; Ozola, V.; Krasikovs, A.; Suna, E. Novel Methods for Preparation of (+)-1-ethyl-4-[2-(4-morpholinyl)ethyl)-3,3-diphenyl-2-pyrrolidinone and Salts Thereof. US2013/109854  A1, 5 May, 2013