Organic electrosynthesis is a versatile and sustainable strategy that harnesses electricity to drive chemical transformations, often replacing harsh reagents or oxidants. This approach allows precise control over reactions, access to unique reactive intermediates, and the ability to create compounds that are challenging or impossible to make using traditional methods. Our research focuses on using anodic oxidation to generate valuable hypervalent halide reagents and applying oxidative decarboxylation to construct C–O, C–N, and C–F bonds.
Publications
64. Electrochemistry of Hypervalent Halogen Compounds
60. Electrochemical synthesis of cyclic biaryl λ3-bromanes from 2,2’-dibromobiphenyls
57. Entry to 2-aminoprolines via electrochemical decarboxylative amidation of N‑acetylamino malonic acid monoesters
DOI: 10.3762/bjoc.21.50
47. Electrochemical Synthesis of Unnatural Amino Acids via Anodic Decarboxylation of N-Acetylamino Malonic Acid Derivatives
DOI: https://doi.org/10.1021/acs.orglett.3c02687.
42. Simple and scalable electrosynthesis of 1H-1-hydroxy-quinazolin-4-ones
40. Electrochemistry and Reactivity of Chelation-stabilized Hypervalent Bromine(III) Compounds
34. Electrochemical Generation of Hypervalent Bromine(III) Compounds
26. Simple and scalable electrochemical synthesis of 2,1-benzisoxazoles and quinoline N-oxides
DOI: 10.1039/C9CC06054E
19. Synthesis of Benzoxazoles Using Electrochemically Generated Hypervalent Iodine
Koleda, O.; Broese, T.; Noetzel, J.; Roemelt, M.; Suna, E.; Francke, R. J. Org. Chem. 2017, 82, 11669–11681.
