{"id":2715,"date":"2018-04-26T21:52:29","date_gmt":"2018-04-26T19:52:29","guid":{"rendered":"https:\/\/ospt.osi.lv\/?page_id=2715"},"modified":"2024-01-28T12:45:20","modified_gmt":"2024-01-28T10:45:20","slug":"front-page","status":"publish","type":"page","link":"https:\/\/ospt.osi.lv\/","title":{"rendered":"Front page"},"content":{"rendered":"

[vc_row el_id=”research-interests” css=”.vc_custom_1524776561733{margin-bottom: 20px !important;padding-top: -20px !important;padding-bottom: 50px !important;background-color: #ffffff !important;border-radius: 10px !important;}”][vc_column width=”1\/12″][\/vc_column][vc_column width=”10\/12″][vc_row_inner css=”.vc_custom_1524776305046{background-color: #ffffff !important;}”][vc_column_inner][vc_column_text]<\/p>\n

Research topics<\/span><\/span><\/h2>\n

[\/vc_column_text]

\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article>
\t\t
<\/canvas>
\n\t\t\t<\/svg>\n \t<\/div><\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div><\/div>\t<\/article><\/div><\/div><\/section>[\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=”1\/12″][\/vc_column][\/vc_row][vc_row el_id=”services”][vc_column][vc_column_text]<\/p>\n

Provided services<\/span><\/h2>\n

[\/vc_column_text][vc_row_inner equal_height=”yes” gap=”20″][vc_column_inner el_class=”ospt-shadow-div ospt-round-div” width=”1\/3″ css=”.vc_custom_1524944677721{padding-bottom: 10px !important;background-color: #ffffff !important;}”]

\n\t\t\t<\/svg>\n \t<\/div><\/div><\/div>
\n

Drug discovery projects on a contract research base<\/span><\/h3>\n

\n<\/div><\/div>

View Projects<\/a><\/div><\/div><\/div>[\/vc_column_inner][vc_column_inner el_class=”ospt-shadow-div ospt-round-div” width=”1\/3″ css=”.vc_custom_1524948104681{padding-bottom: 10px !important;background-color: #ffffff !important;}”]
\n\t\t\t<\/svg>\n \t<\/div><\/div><\/div>
\n

Development of synthetic routes for large scale synthesis<\/span><\/h3>\n

\n<\/div><\/div>

View projects<\/a><\/div><\/div><\/div>[\/vc_column_inner][vc_column_inner el_class=”ospt-shadow-div ospt-round-div” width=”1\/3″ css=”.vc_custom_1524778014945{background-color: #ffffff !important;}”]
\n\t\t\t<\/svg>\n \t<\/div><\/div><\/div>
\n

Custom synthesis of screening compounds<\/span><\/h3>\n

\n<\/div><\/div><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” el_id=”latest-news”][vc_column][vc_column_text]<\/p>\n

Latest news<\/span><\/h2>\n

[\/vc_column_text][cws_sc_time_line filter_by=”cat” cats=”news” post_pp=”8″ count=”8″ hide_cat=”1″ type=”small_type” chars_count=”120″ title=”Latest posts”]

<\/i> View all news<\/a><\/div>[\/vc_column][\/vc_row][vc_row full_width=”stretch_row_content” el_id=”publications”][vc_column][vc_column_text]<\/p>\n

Recent publications<\/span><\/h2>\n

[\/vc_column_text][vc_row_inner][vc_column_inner offset=”vc_col-xs-12″]

\t\t
\r\n\t\t\t
<\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div>\t\t<\/div>\r\n\t<\/div><\/div>

51. Chiral 4-MeO-Pyridine (MOPY) Catalyst for Enantioselective Cyclopropanation: Attenuation of Lewis Basicity Leads to Improved Catalytic Efficiency<\/a><\/h3>

[vc_row][vc_column][vc_column_text]Kluga R., Kinens A., Suna E. Chem. Eur. J. <\/span><\/em>2024<\/span><\/strong>, e202301136
\nDOI: 10.1002\/chem.202301136<\/a>.<\/p>\n

 <\/p>\n

Read More <\/i><\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/article>

\t\t
\r\n\t\t\t
<\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div>\t\t<\/div>\r\n\t<\/div><\/div>

50. Development of novel \u03b22-adrenergic receptor agonists for the stimulation of glucose uptake \u2013 The importance of chirality and ring size of cyclic amines<\/a><\/h3>

[vc_row][vc_column][vc_column_text]Jaunsleine, K.; Supe, L.; Spura, J.; van Beek, S.; Sandstr\u00f6m, A.; Olsen, J.; Halleskog, C.; Bengtsson, T.; Mutule, I.; Pelcman, B. Bioorganic & Medicinal Chemistry Letters 2024<\/strong>, 97, 129562. DOI: 10.1016\/j.bmcl.2023.129562<\/a>.<\/p>\n

 <\/p>\n

Read More <\/i><\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/article>

\t\t
\r\n\t\t\t
<\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div>\t\t<\/div>\r\n\t<\/div><\/div>

49. Synthesis and Evaluation of Novel 5-O-(4-C-Aminoalkyl-\u03b2-D-ribofuranosyl) Apramycin Derivatives for the Inhibition of Gram-Negative Pathogens Carrying the Aminoglycoside Phosphotransferase(3\u2032)-Ia Resistance Determinant<\/a><\/h3>

[vc_row][vc_column][vc_column_text]Lubriks, D.; Haldimann, K.; Kili\u00e7, F.; Hartmann, M.; B\u00f6ttger, E. C.; Hobbie, S. N.; Suna, E.; Crich, D. Helv. Chim. Acta\u00a0<\/span><\/em>2023<\/span><\/strong>, e202300138<\/span>
\nDOI: 10.1002\/hlca.202300138<\/a>.<\/p>\n

 <\/p>\n

Read More <\/i><\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/article>

\t\t
\r\n\t\t\t
<\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div>\t\t<\/div>\r\n\t<\/div><\/div>

48. Pyrazolidinone-based peptidomimetic SARS-CoV-2 Mpro inhibitors<\/a><\/h3>

[vc_row][vc_column][vc_column_text]Jelisejevs D., Bula A. L., Kinena L. Bioorg. Med. Chem. Lett. <\/span><\/em>2023<\/span><\/strong>, 96<\/em>, 129530
\nDOI: 10.1016\/j.bmcl.2023.129530<\/a>.<\/p>\n

 <\/p>\n

Read More <\/i><\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/article>

\t\t
\r\n\t\t\t
<\/div>
\n\t\t\t<\/svg>\n \t<\/div><\/a>
\n\t\t\t<\/svg>\n \t<\/div><\/a><\/div><\/div>\t\t<\/div>\r\n\t<\/div><\/div>

47. Electrochemical Synthesis of Unnatural Amino Acids via Anodic Decarboxylation of N-Acetylamino Malonic Acid Derivatives<\/a><\/h3>

[vc_row][vc_column][vc_column_text]Koleda O., Prane K., Suna E. Org. Lett.<\/em> 2023, <\/span><\/strong>25 (<\/em><\/span>44)<\/span>,<\/em> 7958\u20137962<\/span>.
\nDOI: https:\/\/doi.org\/10.1021\/acs.orglett.3c02687<\/a>.<\/p>\n

 <\/p>\n

Read More <\/i><\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/article><\/div><\/div><\/section>[\/vc_column_inner][\/vc_row_inner][vc_row_inner css=”.vc_custom_1524775622933{margin-bottom: 5px !important;padding-bottom: 30px !important;background-color: #ffffff !important;border-radius: 10px !important;}” el_class=”ospt-shadow”][vc_column_inner offset=”vc_col-xs-12″]

<\/i> View all publications<\/a><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row el_id=”research-interests” css=”.vc_custom_1524776561733{margin-bottom: 20px !important;padding-top: -20px !important;padding-bottom: 50px !important;background-color: #ffffff !important;border-radius: 10px !important;}”][vc_column width=”1\/12″][\/vc_column][vc_column width=”10\/12″][vc_row_inner css=”.vc_custom_1524776305046{background-color: #ffffff !important;}”][vc_column_inner][vc_column_text] Research topics [\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=”1\/12″][\/vc_column][\/vc_row][vc_row el_id=”services”][vc_column][vc_column_text] Provided services [\/vc_column_text][vc_row_inner equal_height=”yes” gap=”20″][vc_column_inner el_class=”ospt-shadow-div ospt-round-div” width=”1\/3″ css=”.vc_custom_1524944677721{padding-bottom: 10px !important;background-color: #ffffff !important;}”][\/vc_column_inner][vc_column_inner el_class=”ospt-shadow-div ospt-round-div” width=”1\/3″ css=”.vc_custom_1524948104681{padding-bottom: 10px !important;background-color: #ffffff !important;}”][\/vc_column_inner][vc_column_inner el_class=”ospt-shadow-div ospt-round-div” width=”1\/3″ css=”.vc_custom_1524778014945{background-color: #ffffff !important;}”][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” el_id=”latest-news”][vc_column][vc_column_text] Latest news [\/vc_column_text][cws_sc_time_line […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/pages\/2715"}],"collection":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/comments?post=2715"}],"version-history":[{"count":4,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/pages\/2715\/revisions"}],"predecessor-version":[{"id":4276,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/pages\/2715\/revisions\/4276"}],"wp:attachment":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/media?parent=2715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}