{"id":2667,"date":"2015-02-23T15:08:07","date_gmt":"2015-02-23T13:08:07","guid":{"rendered":"https:\/\/ospt.osi.lv\/?p=2667"},"modified":"2022-01-11T12:13:42","modified_gmt":"2022-01-11T10:13:42","slug":"stereoselective-synthesis-of-the-diazonamide-a-macrocyclic-core","status":"publish","type":"post","link":"https:\/\/ospt.osi.lv\/stereoselective-synthesis-of-the-diazonamide-a-macrocyclic-core\/","title":{"rendered":"14. Stereoselective Synthesis of the Diazonamide A Macrocyclic Core"},"content":{"rendered":"<p>Mutule, I.; Joo, B.; Medne, Z.; Kalnins, T.; Vedejs, E.; Suna, E. <em>J. Org. Chem.<\/em> <strong>2015<\/strong>, <em>80<\/em>, 3058-3066.<\/p>\n<p>DOI: <a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jo5029419\" target=\"_blank\" rel=\"noopener\">10.1021\/jo502941<\/a><\/p>\n<p><!--more--><\/p>\n<h4>Abstract<\/h4>\n<p>Stereoselective synthesis of the right-hand heteroaromatic macrocycle of diazonamide A features C16\u2013C18 bond formation in the Suzuki\u2013Miyaura cross-coupling and atropodiastereoselective Dieckmann-type macrocyclization as key steps. The Suzuki\u2013Miyaura cross-coupling gave the best yields when it was catalyzed by a palladium\u2013dioxygen complex.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mutule, I.; Joo, B.; Medne, Z.; Kalnins, T.; Vedejs, E.; Suna, E. J. Org. Chem. 2015, 80, 3058-3066. DOI: 10.1021\/jo502941<\/p>\n","protected":false},"author":1,"featured_media":2668,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[16,42],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/2667"}],"collection":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/comments?post=2667"}],"version-history":[{"count":1,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/2667\/revisions"}],"predecessor-version":[{"id":3987,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/2667\/revisions\/3987"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/media\/2668"}],"wp:attachment":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/media?parent=2667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/categories?post=2667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/tags?post=2667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}