{"id":3650,"date":"2019-10-15T08:12:52","date_gmt":"2019-10-15T06:12:52","guid":{"rendered":"https:\/\/ospt.osi.lv\/?p=3650"},"modified":"2022-01-11T12:15:36","modified_gmt":"2022-01-11T10:15:36","slug":"simple-and-scalable-electrochemical-synthesis-of-21-benzisoxazoles-and-quinoline-n-oxides","status":"publish","type":"post","link":"https:\/\/ospt.osi.lv\/simple-and-scalable-electrochemical-synthesis-of-21-benzisoxazoles-and-quinoline-n-oxides\/","title":{"rendered":"26. Simple and scalable electrochemical synthesis of 2,1-benzisoxazoles and quinoline N-oxides"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]Rodrigo, E.; Baunis, H.; Suna, E.; Waldvogel, S., R. <em>Chem. Commun.<\/em>, <strong>2019<\/strong>, <em>55<\/em>, 12255-1225.<\/p>\n<p>DOI: <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2019\/CC\/C9CC06054E#!divAbstract\"><span class=\"list__item-data\">10.1039\/C9CC06054E<\/span><\/a><\/p>\n<p><!--more--><\/p>\n<h4>Abstract<\/h4>\n<p style=\"text-align: justify;\">Cathodic reduction of the nitro moiety and subsequent intramolecular cyclization affords different substituted 2,1-benzisoxazoles and quinoline <em>N<\/em>-oxides. This methodology allows the synthesis of two different types of heterocycles from common simple starting materials, using electrons as a sole reagent for this transformation. The electrolysis can be conducted in a very simple undivided electrolysis cell under constant current conditions. This permits working on a larger scale compared to other electrochemical methodologies and represents a significant advantage.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text]Rodrigo, E.; Baunis, H.; Suna, E.; Waldvogel, S., R. Chem. Commun., 2019, 55, 12255-1225. DOI: 10.1039\/C9CC06054E<\/p>\n","protected":false},"author":1,"featured_media":3651,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[43,16],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/3650"}],"collection":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/comments?post=3650"}],"version-history":[{"count":1,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/3650\/revisions"}],"predecessor-version":[{"id":3999,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/3650\/revisions\/3999"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/media\/3651"}],"wp:attachment":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/media?parent=3650"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/categories?post=3650"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/tags?post=3650"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}