{"id":4041,"date":"2022-06-17T14:24:43","date_gmt":"2022-06-17T12:24:43","guid":{"rendered":"https:\/\/ospt.osi.lv\/?p=4041"},"modified":"2022-11-16T09:04:03","modified_gmt":"2022-11-16T07:04:03","slug":"synthetic-approach-toward-enantiopure-cyclic-sulfinamides","status":"publish","type":"post","link":"https:\/\/ospt.osi.lv\/synthetic-approach-toward-enantiopure-cyclic-sulfinamides\/","title":{"rendered":"39. Synthetic Approach toward Enantiopure Cyclic Sulfinamides"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]Jersovs, G.; Bojars, M.; Donets, P., A.; Suna, E. <em>Org. Lett.<\/em> <strong>2022<\/strong>,<em> 24, <\/em>4625\u20134629.<\/p>\n<p>DOI: <a title=\"Synthetic Approach toward Enantiopure Cyclic Sulfinamides\" href=\"https:\/\/doi.org\/10.1021\/acs.orglett.2c01738\" target=\"_blank\" rel=\"nofollow noopener\">10.1021\/acs.orglett.2c01738<\/a><\/p>\n<p><!--more--><\/p>\n<h4>Abstract<\/h4>\n<p style=\"text-align: justify;\">A synthetic approach toward densely substituted enantiopure cyclic sulfinamides possessing up to four consecutive stereogenic centers was developed based on a completely diastereoselective S<sub>N<\/sub>2\u2032 cyclization\/<i>tert<\/i>-Bu cleavage sequence. Diastereospecific transformation of the obtained scaffold into chiral S<sup>VI<\/sup> derivatives such as sulfoximines and sulfonimidamides is demonstrated.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text]Jersovs, G.; Bojars, M.; Donets, P., A.; Suna, E. Org. Lett. 2022, 24, 4625\u20134629. DOI: 10.1021\/acs.orglett.2c01738<\/p>\n","protected":false},"author":1,"featured_media":4043,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[44,16],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/4041"}],"collection":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/comments?post=4041"}],"version-history":[{"count":3,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/4041\/revisions"}],"predecessor-version":[{"id":4090,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/posts\/4041\/revisions\/4090"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/media\/4043"}],"wp:attachment":[{"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/media?parent=4041"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/categories?post=4041"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ospt.osi.lv\/wp-json\/wp\/v2\/tags?post=4041"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}