Dr. Artis Kinens

Dr. Artis Kinens

Former PhD student, Scientist

Curriculum Vitae

Education

PhD in chemistry, University of Latvia, 2019
Thesis: “Lewis base catalysis by chiral DMAP species”
Supervisor: Prof. Dr. E. Suna

MSc in chemistry, Riga Technical University, 2009
Thesis: “Synthesis of homochirl diamines and aminophenoles”
Supervisor: Prof. Dr. E. Suna

Experience

Latvian Institute of Organic Synthesis
Researcher, 2020-present
Research Assistant, 2009-2020
Laboratory Assistant, 2005-2009

University of Latvia
Associate professor, 2023-present
Assistant to professor, 2020-2023
Lecturer, 2017-2020
Teaching assistant, 2015-2017

Imperial College London, UK
Visiting Researcher, 2022 (4 months)
(advisor Prof. A. C. Spivey)

University of Michigan, USA
Visiting Researcher, 2014 (5 months)
(advisor Prof. E. Vedejs)

University of Michigan, USA
Visiting Researcher, 2009 (4 months), 2010 (4 months)
(advisor Prof. E. Vedejs)

Honors and Awards

Solomon Hiller prize, JSC Olainfarm and Latvian Academy of Sciences and Riga Technical University Development fund, 2019

Award for the best achievement in Latvian science of 2019, Latvian Academy of Sciences, 2019

Publications

  1. Mazarevics, A.; Kinens, A.; Leduskrasts, K.; Suna, E. “Tailoring Emission Lifetime for Dopant-Induced Phosphorescence” ACS Materials Lett. 2024, 6, 4590–4595, DOI: 10.1021/acsmaterialslett.4c01412
  2. Stakanovs, G.; Rasina, D.; Belyakov, S.; Kinens, A.; Jirgensons. A. “Bridgehead epoxide iso-euphoranin E from β-caryophyllene oxide via sequential cationic formation and scission of [4.3.2]propellane” Org. Chem. Front. 2024, 11, 5086-5092, DOI: 10.1039/D4QO00940A
  3. Kalnins, T.; Vitkovska, V.; Kazak, M.; Zelencova-Gopejenko, D.; Ozola, M.; Narvaiss, N.; Makrecka-Kuka, M.; Domračeva, I.; Kinens, A.; Gukalova, B.; Konrad, N.; Aav, R.; Bonato, F.; Lucena-Agell, D.; Díaz, J., F.; Liepinsh, E.; Suna, E. “Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide” J. Med. Chem. 2024, 67, 9227–9259, DOI: 10.1021/acs.jmedchem.4c00388
  4. Cizikovs, A.; Basens, E., E.; Zagorska, P. A.; Kinens, A.; Grigorjeva, L. “Indole Synthesis by Cobalt-Catalyzed Intramolecular Amidation via the Oxidatively Induced Reductive Elimination Pathwa” ACS Catal. 2024, 14, 1690−1698, DOI: 10.1021/acscatal.3c05706
  5. Kluga, R.; Kinens, A.; Suna, E. “Chiral 4-MeO-Pyridine (MOPY) Catalyst for Enantioselective Cyclopropanation: Attenuation of Lewis Basicity Leads to Improved Catalytic Efficiency” Chem. Eur. J. 2024, e202301136, DOI: 10.1002/chem.202301136
  6. Leduskrasts, K.; Kinens, A.; Suna, E. “The emission efficiency of cationic solid state luminophores is directly proportional to the intermolecular charge transfer intensity” Chem. Commun. 2023, 59, 6905 – 6908. DOI: 10.1039/d3cc01674a
  7. Melngaile, R.; Videja, M.; Kuka, J.; Kinens, A.; Zacs, D.; Veliks, J. “Synthetic Access to Fluorocyclopropylidenes” Org. Lett. 2023, 25, 13, 2280–2284. DOI: 10.1021/acs.orglett.3c00579
  8. Leitis, Z.; Sakaine, G.; Kinens, A.; Smits, G. “Stereoselective Olefination with Sterically Demanding Julia–Kocienski Reagents: Total Synthesis of Oxo-prothracarcin, Oxo-tomaymycin, and Boseongazepine B” ACS Omega 2022, 7, 30519–30534. DOI: 10.1021/acsomega.2c03732
  9. Kinens, A.; Balkaitis, S.; Ahmad, O. K.; Piotrowski, D. W.; Suna, E. “Acylative Dynamic Kinetic Resolution of Secondary Alcohols: Tandem Catalysis by HyperBTM and Bäckvall’s Ruthenium Complex” J. Org. Chem. 2021, 86, 7189–7202.  DOI: 10.1021/acs.joc.1c00545
  10. Gulbe, K.; Lugiņina, J.; Jansons, E.; Kinens, A.; Turks, M. “Metal-free glycosylation with glycosyl fluorides in liquid SO2” Beilstein J. Org. Chem. 2021, 17, 964-976. DOI: 10.3762/bjoc.17.78
  11. Veliks, J.; Videja, M.; Kinens, A.; Bobrovs, R.; Priede, M.; Kuka, J. “trans-Fluorine Effect in Cyclopropane: Diastereoselective Synthesis of Fluorocyclopropyl Cabozantinib Analogs” ACS Med. Chem. Lett. 2020, 11, 2146–2150. DOI: 10.1021/acsmedchemlett.0c00220
  12. Leduskrasts, K.; Kinens, A.; Suna, E. “Cation–π interactions secure aggregation induced emission of planar organic luminophores” Chem. Commun., 2019, 55, 12663-12666. DOI: 10.1039/C9CC06829E
  13. Kinens, A.; Balkaitis, S.; Suna, E. “Preparative-Scale Synthesis of Vedejs Chiral DMAP Catalysts” J. Org. Chem. 2018, 83, 12449–12459. DOI: 10.1021/acs.joc.8b01687
  14. Kinens, A.; Sejejs, M.; Kamlet, A. S.; Piotrowski, D. W.; Vedejs, E.; Suna, E. “Development of a Chiral DMAP Catalyst for the Dynamic Kinetic Resolution of Azole Hemiaminals” J. Org. Chem. 2017, 82, 869–886. DOI: 10.1021/acs.joc.6b02955
  15. Smits, G.; Kinens, A.; Zemribo, R. “Ireland–Claisen Rearrangement of 6-Methylene-1,4-oxazepan-2-ones” Eur. J. Org. Chem. 2015, 6701–6709 DOI: 10.1002/ejoc.201500918
  16. Grigorjeva, L.; Kinens, A.; Jirgensons, A.  “Unsaturated syn- and anti-1,2-Amino Alcohols by Cyclization of Allylic Bis-trichloroacetimidates. Stereoselectivity Dependence on Substrate Configuration” J. Org. Chem. 2015, 80, 920–927. DOI: 10.1021/jo502404y
  17. Kinens, A.; Kalnins, T.; Suna, E. “Synthesis of 9-Phenylacridines via Ortho-Lithiation–Cyclization Sequence” Chem. Heterocycl. Comp. 2015, 50, 1501-1505. DOI: 10.1007/s10593-014-1616-y