Curriculum Vitae
Education
PhD in chemistry, University of Latvia, 2020
Thesis: “Design and Synthesis of Aspartic Protease Inhibitors as Antimalarial Agents”
Supervisor: Dr.chem. Vita Ozola
MSc in chemistry, University of Latvia, 2010
Thesis: “Rearrangement of N-benzoxazolylcysteine derivatives”
Supervisor: Dr.chem. Vita Ozola
Experience
Latvian Institute of Organic Synthesis
Research Assistant, 2010-present
Laboratory Assistant, 2006-2010
Publications
- Kinena, L.; Ozola, V. “Tetrahydroisoquinoline-Based Non-Peptidomimetic Plasmepsin Inhibitors” Chem. Heterocycl. Comp. 2020, 56, 60–66. DOI: 10.1007/s10593-020-02623-6
- Zogota, R.; Kinena, L.; Withers-Martinez, C.; Blackman, M., J.; Bobrovs, R.; Pantelejevs, T.; Kanepe-Lapsa, I.; Ozola, O.; Jaudzems, K.; Suna, E.; Jirgensons, A. “Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D” Eur. J. Med. Chem. 2019, 163, 344-352. DOI: 10.1016/j.ejmech.2018.11.068
- Kinena, L.; Leitis, G.; Kanepe-Lapsa, I.; Bobrovs, R.; Jaudzems. K.; Ozola, V.; Suna, E.; Jirgensons, A. “Azole‐based non‐peptidomimetic plasmepsin inhibitors” Arch. Pharm. Chem. Life Sci. 2018, 351, 1800151. DOI: 10.1002/ardp.201800151
Patents
- Kinena, L.; Ozola, V.; Suna, E.; Leitis, G.; Jirgensons, A.; Jaudzems, K.; Kanepe-Lapsa, I.; Domracheva, I. 2. Substituted aminoalkylazoles as malarial aspartic protease inhibitors. WO 2017069601 A1, 27 Apr, 2017