20. Stereodivergent Synthesis of Pseudotabersonine Alkaloids

Kazak, M.; Priede, M.; Shubin, K.; Bartrum, H. E.; Poisson, J.-F.; Suna, E. Org. Lett. 2017, 19, 5356–5359.

DOI: 10.1021/acs.orglett.7b02635

Abstract

An eight-step stereodivergent synthesis of enantiomerically pure (−)-14-epi-pseudotabersonine and (+)-pseudotabersonine has been developed from a common Ntert-butanesulfinyl ketimine key intermediate.


Date: Sep 13, 2017
AUTHOR: Artis Kinens
Diastereoselective synthesis, Publications, Total synthesis