Kinena, L.; Ozola, V. Chem. Heterocycl. Comp. 2020, 56, 60–66.
DOI: 10.1007/s10593-020-02623-6
Abstract
A series of tetrahydroisoquinoline derivatives containing different aryl substituents were designed and synthesized using Pictet–Spengler reaction as the key step. The synthesized tetrahydroisoquinoline derivatives displayed micromolar inhibitory activity against plasmepsins I and II.
Date: Jun 12, 2020
AUTHOR: Artis Kinens